Pharma company: pascual laboratories

List of pascual laboratories products:

• Aciclovir - Pharmacological action Aciclovir is an antiviral agent. Thymidine kinase of virus-infected cells actively converts acyclovir through a series of sequential reactions in the mono-, di- and triphosphate of acyclovir. The latter interacts with the viral DNA polymerase, and embedded in DNA, which is synthesized for new viruses. Thus it is formed a "defective" viral DNA which leads to suppression of replication of new generations of viruses. This mediciine acyclovir is active against Herpes...
• Alphagram
• Amlodipine - Amlodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, amlodipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth...
• Amoxicillin - 1.1 Infections of the Ear, Nose, and Throat Amoxicillin tablets are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus species. (α- and β-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae. 1.2 Infections of the Genitourinary Tract Amoxicillin tablets are indicated in the treatment of infections due to susceptible (ONLY...
• Antamin
• Aplosyn
• Aplosyn C
• Aplosyn HP
• Aplosyn N
• Aplosyn Otic
• Arpimune
• Bideren
• C-Lium Fibre
• Carbocisteine
• Cefaclor - SPL UNCLASSIFIED SECTION CEFACLOR CAPSULES, USP Rev. 09/15 Rx Only To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefaclor and other antibacterial drugs, cefaclor should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
• Cefalexin
• Ceftazidime - SPL UNCLASSIFIED SECTION TAZICEF ® brand of ceftazidime for injection, USP                                                                    PRESCRIBING INFORMATION ...
• Ceftriaxone - SPL UNCLASSIFIED SECTION Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection, USP and other antibacterial drugs, Ceftriaxone for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
• Cefuroxime - PHARMACY BULK PACKAGE NOT FOR DIRECT INFUSION Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefuroxime for Injection, USP and other antibacterial drugs, Cefuroxime for Injection, USP should be used only to treat or...
• Celecoxib - Celecoxib information Celecoxib is a NSAIDs medicine (Non-steroidal anti inflammatory drug). As a NSAID drug, Celecoxib fights against inflammation, pain or swelling by reducing the amount of substances that cause them. Celecoxib indications This medication is usually prescribed to patients who suffer from Stiffness, pain or inflammation which may accompany Osteoarthritis or rheumatoid arthritis. Celecoxib helps ease these symptoms while also decreasing the amount of polyps from your...
• Chloramphenicol - DESCRIPTION : Chloramphenicol is a broad-spectrum antibiotic shown to have specific therapeutic activity against a wide variety of organisms.  Its activity was first demonstrated in culture filtrates from a species of soil organism collected in Venezuela, later designated as Streptomyces venezuelae .  The antibiotic was subsequently isolated from culture filtrates (1), identified chemically (2), and later synthesized (3). ...
• Ciprofloxacin - Chemical Structure WARNING Fluoroquinolones, including Ciprofloxacin Tablets, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants (See WARNINGS ). ...
• Clarithromycin - DESCRIPTION Clarithromycin is a semi-synthetic macrolide antibiotic. Chemically, it is 6-0-methylerythromycin. The molecular formula is C 38 H 69 NO 13 , and the molecular weight is 747.96. CLINICAL PHARMACOLOGYPharmacokinetics Clarithromycin is rapidly absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability...
• Clindamycin - ZydaClin™ (clindamycin) Oral Drops liquid For Use in Dogs & Cats Equivalent to 25 mg per mL clindamycin ...
• Cloxacillin - A semi-synthetic antibiotic that is a chlorinated derivative of oxacillin. [PubChem] Indication: Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci. Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is for use against staphylococci that produce beta-lactamase.
• Co-Trimoxazole - Pharmacological action Co-Trimoxazole Pharmaniaga is a synthetic antimicrobial drug with broad spectrum bactericidal action. sulfamethoxazole has a bacteriostatic action, which is associated with inhibition of recycling process of PABA and a violation dihydrofolic acid's synthesis in bacterial cells. Trimethoprim inhibits the enzyme that is involved in the metabolism of folic acid converting dihydrofolate to tetrahydrofolate. Thus it is blocked two successive stages of the biosynthesis of...
• Continukit
• Cor
• Dexanicol
• Dexeryl
• Dilatam
• Dilatam SR
• Diphenhydramine - Pharmacological action Diphenhydramine Xepa-Soul Pattinson is a blocker of histamine H1-receptors. It has antiallergic activity, has a local anesthetic, antispasmodic and mild ganglion blocking action. When Diphenhydramine Xepa-Soul Pattinson administered orally diphenhydramine has a sedative and hypnotic effects, has a moderate antiemetic effect and has a central holinoliticheskoy activity. When applied externally it has antiallergic effect. Pharmacokinetics Diphenhydramine...
• Diumide-K
• Econofix
• Econokit
• Econokit-MDR
• Econopack
• Enalapril - Enalapril information Enalapril is one of the most effective anti-hypertensive drugs in the market. Belonging to the angiotensin-converting-enzyme inhibitors (ACE inhibitors) category of drugs, Enalapril helps to keep raising blood pressure under control thereby reducing the risk factors of this disease. Since hypertension works out the heart muscles to cause early arterial failure, Enalapril stands in the way and helps to keep your heart healthy, indirectly. Like all other ACE inhibitors,...
• Erythromycin - SPL UNCLASSIFIED SECTION Film-coated Tablets Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Erythromycin Tablets and other antibacterial drugs, Erythromycin Tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
• Ethambutol - An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863) Indication: For use, as an adjunct, in the treatment of pulmonary tuberculosis. Ethambutol is an oral chemotherapeutic agent which is specifically...
• Eundin
• Facetam
• Glocure-Opta
• Glucolyte
• Glucolyte Plus
• Glucost
• Glutaphos
• Hydrocortisone - Active Ingredients: Hydrocortisone Acetate 0.50% Purpose Anti-itch Uses: to soothe: • skin irritations • itching • dermatitis • eczema • flea bites. Warnings For external use only on adult dogs. ...
• Hypace
• I-Tab
• Immuvit
• Irinotesin
• Isoniazid - SPL UNCLASSIFIED SECTION Rev. 02/11 Rx Only WARNING Severe and sometimes fatal hepatitis associated with isoniazid therapy has been reported and may occur or may develop even after many months of treatment. The risk of developing hepatitis is age related. Approximate case rates by age are: less than 1 per 1,000 for persons under 20 years of age, 3 per 1...
• Isoxin
• Itex - Pharmacological action Ofloxacin is an antimicrobial agents of broad-spectrum action type from fluoroquinolone group. Bactericidal action of ofloxacin is due to blockage of the enzyme DNA gyrase in bacterial cells. This medication is highly active against most of gram-negative bacteria: Escherichia coli, Salmonella spp., Shigella spp., Proteus spp., Morganella morganii, Klebsiella spp. (including Klebsiella pneumoniae), Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp.,...
• Lezasin
• Lonace
• Losartan - Losartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the...
• Mefenamic Acid - SPL UNCLASSIFIED SECTION Rx only WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS SPL UNCLASSIFIED SECTION Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased...
• Meloxicam - WARNING: RISK OF SERIOUS CARDIOVASCULAR and GASTROINTESTINAL EVENTS Cardiovascular Risk Nonsteroidal anti-inflammatory drugs (NSAIDs) may cause an increased risk of serious cardiovascular (CV) thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use....
• Metformin - Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin is the only oral antihyperglycemic agent that is not associated with weight gain. Metformin may induce weight loss and is the drug of choice for obese NIDDM patients. When used alone, metformin does not cause hypoglycemia;...
• Metoprolol - Pharmacological action Metoprolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic effect. Metoprolol decreases automaticity of sinus node, reducing heart rate, slows AV-conduction, decreases myocardial contractility and excitability, reduces cardiac output, reduces myocardial oxygen demand. This drug inhibits the stimulatory effect of catecholamines on the heart during physical and...
• Metronidazole - Pharmacological action Metronidazole is an anti protozoal agent. It is believed that the mechanism of action is associated with DNA damage-sensitive microorganisms. Active against Trichomonas vaginalis, Gardnerella vaginalis, Giardia lamblia, Entamoeba histolytica, and obligate anaerobic bacteria (including Bacteroides spp., Fusobacterium spp.). Aerobic bacteria are resistant to metronidazole. In combination with amoxicillin Metronidazole is active against Helicobacter pylori. It is...
• Naproxen - Naproxen information Naproxen is an anti-inflammatory non-steroidal anti-inflammatory (NSAID) medicine. Naproxen Pascual Laboratories's actions help reduce the chemicals found in the patient's organism that are usually responsible for the triggering of inflammation and pain. Naproxen indications Naproxen is a drug normally prescribed in the treatment of pain, stiffness or inflammation that are usually triggered by medical disorders such as Gout, Osteoarthritis, menstruation abdominal...
• Neotigason
• Nodiz
• Norbloc
• Norfloxacin - A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase. [PubChem] Indication: For the treatment of urinary tract infection Norfloxacin is a quinolone/fluoroquinolone antibiotic. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to...
• Ofloxacin - Pharmacological action Ofloxacin is an antimicrobial agents of broad-spectrum action type from fluoroquinolone group. Bactericidal action of ofloxacin is due to blockage of the enzyme DNA gyrase in bacterial cells. This medication is highly active against most of gram-negative bacteria: Escherichia coli, Salmonella spp., Shigella spp., Proteus spp., Morganella morganii, Klebsiella spp. (including Klebsiella pneumoniae), Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp.,...
• Optaphen
• Opthagen
• Oracare
• Pactal
• Poten-Cee
• Poten-Cee Forte
• Prenarex Plus
• Primace
• Profenil
• Pyrazinamide - SPL UNCLASSIFIED SECTION Rx only DESCRIPTION: Pyrazinamide, the pyrazine analogue of nicotinamide, is an antituberculous agent. It is a white crystalline powder, stable at room temperature, and sparingly soluble in water. Pyrazinamide has the following structural formula: ...
• Ramitop
• Ranitidine - Pharmacological action Ranitidine is a blocker of histamine H2-receptors. Inhibits basal and stimulated by histamine, gastrin and acetylcholine (to a lesser extent) the secretion of hydrochloric acid. Increases the pH of gastric contents and reduces the activity of pepsin. The duration of action of ranitidine with a single admission - 12 hours. Pharmacokinetics After oral administration, ranitidine is rapidly absorbed from the gastrointestinal tract. Eating and antacids significantly...
• Rifampicin
• Rifzin
• Rifzin F
• Roxithromycin - Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain...
• Senalax
• Simvastatin - Pharmacological action Simvastatin is a hypolipidemic agent from a group of statins, an inhibitor of HMG-CoA reductase. This medication is a prodrug because it has in its structure the closed lactone ring which is hydrolyzed after intake. Lipid-lowering effect of statins is associated with lower levels of total cholesterol by LDL-C. Reducing cholesterol is dose-dependent and is not linear but exponential. Statins do not affect the activity of lipoprotein and hepatic lipase, have no...
• Sindoxplatin
• Sindroxocin
• Syntemax
• Virulex Forte
• Vitamin B-Complex
• Vitamins
• Xetam-Opta
• Zilden
• Zivas - Pharmacological action Zivas is a lipid-lowering drugs of the statin group. An inhibition of HMG-CoA reductase leads to a series of sequential reactions that result in reduced intracellular cholesterol content and it is a compensatory increase in activity of LDL receptors and thus accelerate the catabolism of LDL cholesterol. The lipid-lowering effect of statins is associated with lower levels of total cholesterol by LDL-C. The reduction in LDL cholesterol is dose-dependent and is not...

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The information was verified by Dr. Rachana Salvi, MD Pharmacology