Pharma company: obolenskoe pharmaceutical enterprise

List of obolenskoe pharmaceutical enterprise products:

• Aciclovir - Pharmacological action Aciclovir is an antiviral agent. Thymidine kinase of virus-infected cells actively converts acyclovir through a series of sequential reactions in the mono-, di- and triphosphate of acyclovir. The latter interacts with the viral DNA polymerase, and embedded in DNA, which is synthesized for new viruses. Thus it is formed a "defective" viral DNA which leads to suppression of replication of new generations of viruses. This mediciine acyclovir is active against Herpes...
• Adolor - Pharmacological action Adolor is a NSAID, derivative of pyrrolizine-carboxylic acid. This medication has a marked analgesic effect, also has anti-inflammatory and mild antipyretic action. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Pharmacokinetics After oral administration Adolor is absorbed from the...
• Agregal
• Algezir Ultra - Algezir Ultra information Algezir Ultra is an anti-inflammatory non-steroidal anti-inflammatory (NSAID) medicine. Algezir Ultra's actions help reduce the chemicals found in the patient's organism that are usually responsible for the triggering of inflammation and pain. Algezir Ultra indications Algezir Ultra is a drug normally prescribed in the treatment of pain, stiffness or inflammation that are usually triggered by medical disorders such as Gout, Osteoarthritis, menstruation...
• Algofetin
• Amiodarone - An antianginal and antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting Na,K-activated myocardial adenosine triphosphatase. There is a resulting decrease in heart rate and in vascular resistance. [PubChem] Indication: Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of...
• Analgin
• Anaprilin - Pharmacological action Propranolol is a non-selective beta-blocker. This medication has antihypertensive, antianginal and antiarrhythmic action. The hypotensive effect is associated with a decrease in minute volume of blood, sympathetic stimulation of peripheral vascular disease, decreased activity of the renin-angiotensin system (has a value in patients with initial hypersecretion of renin), sensitivity of baroreceptors of the aortic arch (not going to enhance their activity in response...
• Atenolol - Pharmacological action Atenolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic action. Atenolol reduces the stimulatory effect on the heart sympathetic innervation and circulating catecholamines. The hypotensive effect of this drug is associated with a decrease in minute volume of blood, decreased activity of the renin-angiotensin system (has a greater significance for patients with...
• Butadion
• Captopril - SPL UNCLASSIFIED SECTION CAPTOPRIL TABLETS, USP Rev. 03/16 Rx Only WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue captopril tablets as soon as possible. • Drugs...
• Carbamazepine - WARNINGS SERIOUS DERMATOLOGIC REACTIONS AND HLA-B * 1502 ALLELE SERIOUS AND SOMETIMES FATAL DERMATOLOGIC REACTIONS, INCLUDING TOXIC EPIDERMAL NECROLYSIS (TEN) AND STEVENS-JOHNSON SYNDROME (SJS), HAVE BEEN REPORTED DURING TREATMENT WITH CARBAMAZEPINE. THESE REACTIONS ARE ESTIMATED TO OCCUR IN 1 TO 6 PER 10,000 NEW USERS IN COUNTRIES WITH MAINLY CAUCASIAN POPULATIONS, BUT THE RISK IN SOME ASIAN COUNTRIES IS ESTIMATED TO BE ABOUT 10 TIMES...
• Carvedilol - Carvedilol information Carvedilol is a blood pressure medication and belongs to the class of drugs known as beta-blockers. These beta-blockers affect the circulatory system, which includes the human heart, arteries and veins. Carvedilol indications This medication is used primarily in treating hypertension or high blood pressure. Carvedilol warnings Taking Carvedilol may not be advisable if you have any of the following conditions: asthma heart problems such as low blood pressure...
• Cidocan
• Cinnarizin - Pharmacological action Cinnarizine is a calcium channel blocker class IV with a predominant effect on the brain vessels, a derivative of piperazine. This medication improves cerebral, coronary and peripheral circulation. Cinnarizine violates the entrance of calcium ions into vascular smooth muscle cells. This drug lowers the tone of arteriolar smooth muscle, decreases the vasoconstrictor response to biogenic substances (epinephrine, norepinephrine, bradykinin). Cinnarizine reduces the...
• Ciprofloxacin - Chemical Structure WARNING Fluoroquinolones, including Ciprofloxacin Tablets, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants (See WARNINGS ). ...
• Co-Trimoxazol
• Diara
• Diclofenac - Pharmacological action NSAIDs, a derivative of phenylacetic acid, diclofenac has a pronounced anti-inflammatory, analgesic and mild antipyretic effect. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin...
• Dipyridamole - DESCRIPTION PERSANTINE® (dipyridamole USP) is a platelet inhibitor chemically described as 2,2',2",2"'-[(4,8- Dipiperidinopyrimido[5,4- d ]pyrimidine-2,6-diyl)dinitrilo]-tetraethanol. It has the following structural formula: Dipyridamole is an odorless yellow crystalline powder, having a bitter taste. It is soluble in dilute acids, methanol and chloroform, and practically insoluble in water. PERSANTINE...
• Doxazosin - DESCRIPTION Doxazosin mesylate is a quinazoline compound that is a selective inhibitor of the alpha 1 subtype of alpha adrenergic receptors. The chemical name of doxazosin mesylate is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate. The molecular formula for doxazosin mesylate is C 23 H 25 N 5 O 5 • CH 4 O 3 S and the molecular weight is 547.6. It has the following structure: ...
• Drotaverine - Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Drotaverine has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown drotaverine to be eliminated mainly non-renally. Indication: Used in the treatment of functional bowel disorders and alleviating pain in renal colic. Drotaverine is a spasmolytic...
• Enalapril - Enalapril information Enalapril is one of the most effective anti-hypertensive drugs in the market. Belonging to the angiotensin-converting-enzyme inhibitors (ACE inhibitors) category of drugs, Enalapril helps to keep raising blood pressure under control thereby reducing the risk factors of this disease. Since hypertension works out the heart muscles to cause early arterial failure, Enalapril stands in the way and helps to keep your heart healthy, indirectly. Like all other ACE inhibitors,...
• Epicur
• Euphylline
• Finasteride - 1 INDICATIONS AND USAGE PROSCAR, is a 5α-reductase inhibitor, indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to ( 1.1 ): Improve symptoms Reduce the risk of acute urinary retention Reduce the risk of the need for surgery including transurethral resection of the prostate (TURP)...
• Floracid - Levofloxacin information Levofloxacin is type of drug that belongs to the group of medicines called antiepileptic drug. Levofloxacin indications This medication is indicated to control seizure. The precise way of how Levofloxacin works is not yet known. This medicine may also be used for purposes not mentioned here. Levofloxacin warnings This drug belongs in the FDA pregnancy category C. Levofloxacin may cause severe side effects to an unborn baby. Do not take Levofloxacin...
• Fluconazole - Pharmacological action Fluconazole is an antifungal drug from the group of triazole derivatives. Inhibits the synthesis of ergosterol disrupting the permeability of the cell wall. This medication is active against Candida, Microsporum, Cryptococcus neoformans, Trichophyton. Pharmacokinetics Fluconazole is well absorbed after oral administration. Simultaneous ingestion does not affect absorption. The bioavailability is 90%. Fluconazole is widely distributed in tissues and organs of the...
• Fluoxetine - Pharmacological action Fluoxetine is an antidepressant, propylamine derivative. The mechanism of action is associated with selective blockade of the inverse of neuronal serotonin reuptake in the CNS. Fluoxetine is a weak antagonist of choline, adrenergic and histamine receptors. Unlike most antidepressants fluoxetine apparently does not cause reduction of functional activity of postsynaptic beta-adrenergic receptors. This medication improves mood, reduces anxiety and stress, eliminates...
• Furosemide - Pharmacological action Furosemide is a loop diuretic. This medication violates the reabsorption of sodium and chlorine in the large segment of the ascending loop of Henle. Due to increasing separation of sodium ions occurs secondary (indirect osmotically bound water) increased excretion of water and increased secretion of potassium ions in the distal renal tubule. Simultaneously increased excretion of calcium and magnesium ions. Furosemide has secondary effects caused by the release of...
• Glibenclamide
• Indometacin
• Ionik
• Ionik Retard
• Ketotifen - Active ingredient Ketotifen (0.025%) (equivalent to ketotifen fumarate 0.035%) Purpose Antihistamine Use Temporarily relieves itchy eyes due to pollen, ragweed, grass, animal hair and dander. Warnings Do not use ...
• Klallergine
• Lem
• Levomycetin
• Loperamide - One of the long-acting synthetic antidiarrheals; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally. [PubChem] Indication: For the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with inflammatory bowel disease or gastroenteritis. Also used for reducing the volume of discharge from ileostomies. Loperamide...
• Metoclopramide - Boxed Warning 8/2017 Indications and Usage ( 1 ) 8/2017 Dosage and Administration, Dosage for Gastroesophageal Reflux ( 2.2 ) 8/2017 Dosage and Administration, Dosage for Acute and...
• Mygrepam
• Nicergoline - An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease. [PubChem] Indication: For the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration. Nicergoline is a potent vasodilator (improves brain blood flow). On the cerebral level it prompts a lowering of vascular resistance, an increase in...
• Nifedipine - Pharmacological action Nifedipine is aSelective calcium channel blocker class II, a derivative of dihydropyridine. This medication inhibits the entry of calcium into cardiomyocytes and vascular smooth muscle cells. Nifedipine has antianginal and hypotensive action. This drug lowers the tone of vascular smooth muscle. Nifedipine dilates coronary and peripheral arteries, lowers blood pressure and slightly - myocardial contractility, reduces afterload and myocardial oxygen demand. This...
• Norfloxacin - A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase. [PubChem] Indication: For the treatment of urinary tract infection Norfloxacin is a quinolone/fluoroquinolone antibiotic. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to...
• Norsulfazol
• Ofloxacin - Pharmacological action Ofloxacin is an antimicrobial agents of broad-spectrum action type from fluoroquinolone group. Bactericidal action of ofloxacin is due to blockage of the enzyme DNA gyrase in bacterial cells. This medication is highly active against most of gram-negative bacteria: Escherichia coli, Salmonella spp., Shigella spp., Proteus spp., Morganella morganii, Klebsiella spp. (including Klebsiella pneumoniae), Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp.,...
• Omelar Cardio
• Omeprazole - WARNINGS AND PRECAUTIONS Bone Fracture ( 5.3 ) 09/2010 WARNINGS AND PRECAUTIONS Diminished anti-platelet activity of clopidogrel ( 5.4 ) 01/2011 ...
• Orunit
• Passagix
• Pentoxifylline - Rx only DESCRIPTION Pentoxil ® (Pentoxifylline Extended-release Tablets, USP) for oral administration contain 400 mg of the active drug and the following inactive ingredients: D&C Red No. 27 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, hypromellose USP, magnesium stearate NF, polyethylene glycol NF, polysorbate 80 NF, povidone USP, silicon dioxide NF and titanium dioxide USP, in an extended-release formulation. Pentoxifylline is a tri-substituted xanthine derivative...
• Perinpress
• Piracetam
• Piroxicam - Pharmacological action Piroxicam is a NSAID, refers to a group oxicams. This medication has anti-inflammatory, analgesic and antipyretic effect. The mechanism of action associated with inhibition of the enzyme COX, which leads to inhibition of prostaglandin synthesis from arachidonic acid. Piroxicam inhibits the aggregation of platelets. For systemic use this medicine reduces the pain syndrome. When Piroxicam used externally it weakens or suppresses inflammation and joint pain at rest...
• Potassium Iodide - Active ingredient Potassium iodide (USP) 65 mg Purpose Thyroid blocking Uses Helps prevent radioactive iodine from getting into the thyroid gland during a nuclear radiation emergency. Use along with other emergency measures recommended by public officials. Warnings ...
• Potassium Orotate
• Ranitidine - Pharmacological action Ranitidine is a blocker of histamine H2-receptors. Inhibits basal and stimulated by histamine, gastrin and acetylcholine (to a lesser extent) the secretion of hydrochloric acid. Increases the pH of gastric contents and reduces the activity of pepsin. The duration of action of ranitidine with a single admission - 12 hours. Pharmacokinetics After oral administration, ranitidine is rapidly absorbed from the gastrointestinal tract. Eating and antacids significantly...
• Ribavirin - WARNING: RISK OF SERIOUS DISORDERS AND RIBAVIRIN-ASSOCIATED EFFECTS WARNING: RISK OF SERIOUS DISORDERS AND RIBAVIRINASSOCIATED EFFECTS See full prescribing information for complete boxed warning. Ribavirin monotherapy, including...
• Rimantadine - An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza. [PubChem] Indication: For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults. Rimantadine, a cyclic amine, is a synthetic antiviral drug and a derivate of adamantane, like a similar drug amantadine. Rimantadine is inhibitory to the in vitro replication of influenza A virus isolates from each of the three antigenic subtypes (H1N1, H2H2 and...
• Roxithromycin - Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain...
• Sulfalene
• Sumamecin
• Verapamil - A calcium channel blocker that is a class IV anti-arrhythmia agent. [PubChem] Indication: For the treatment of hypertension, angina, and cluster headache prophylaxis. Verapamil is an L-type calcium channel blocker that also has antiarrythmic activity. The R-enantiomer is more effective at reducing blood pressure compared to the S-enantiomer. However, the S-enantiomer is 20 times more potent than the R-enantiomer at prolonging the PR interval in treating arrhythmias.
• Verospilactone - Pharmacological action Spironolactone is a potassium, magnesium sparing diuretic. This medication is a competitive antagonist of aldosterone on the effect on distal nephron (competes for binding sites on cytoplasmic protein receptors, reduces the synthesis of permeases in the aldosterone-sensitive part of collecting tubules and distal tubules), increases the excretion of Na+, Cl- and water and reduces the excretion of K+ and urea, reduces the titratable acidity of urine. Increased diuresis...
• Zopiclone - Pharmacological action Zopiclone is a sleeping drug from group of cyclopyrrolone derivatives. This drug is "non benzodiazepine" agonist of benzodiazepine receptors. Zopiclone also has sedative, anxiolytic, muscle-relaxing center, anticonvulsant and amnesic properties. Like a derivative of benzodiazepine zopiclone enhances GABA-ergic processes in the brain, interacting with the benzodiazepine receptors, as a result of the increased sensitivity of GABA-receptors to the neurotransmitter....

Visitor reviews

The information was verified by Dr. Rachana Salvi, MD Pharmacology