Pharma company: meliapharm

List of meliapharm products:

• Alendronate-FC - Alendronate belongs to a family of medications known as bisphosphonates . It is used to treat and prevent osteoporosis for postmenopausal women. It is also used to treat osteoporosis for men. Alendronate may also be used to treat and prevent steroid-induced osteoporosis for men and women (osteoporosis caused by taking corticosteroids such as prednisone for long periods of time). It may also be used to treat Paget's disease of the bone for both men and women. It works by increasing the...
• Amlodipine - Amlodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, amlodipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth...
• Atenolol - Pharmacological action Atenolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic action. Atenolol reduces the stimulatory effect on the heart sympathetic innervation and circulating catecholamines. The hypotensive effect of this drug is associated with a decrease in minute volume of blood, decreased activity of the renin-angiotensin system (has a greater significance for patients with...
• Carvedilol - Carvedilol information Carvedilol is a blood pressure medication and belongs to the class of drugs known as beta-blockers. These beta-blockers affect the circulatory system, which includes the human heart, arteries and veins. Carvedilol indications This medication is used primarily in treating hypertension or high blood pressure. Carvedilol warnings Taking Carvedilol may not be advisable if you have any of the following conditions: asthma heart problems such as low blood pressure...
• Citalopram - Pharmacological action Citalopram is an antidepressant. The mechanism of action is associated with selective blockade of the inverse of neuronal serotonin in the synapses of neurons of the CNS. Citalopram lacks or has a very weak ability to bind to histamine, m-choline- and adrenoreceptors. Pharmacokinetics After oral administration C max of citalopram in plasma is achieved within 2-4 hours. The oral bioavailability is about 80%. Changes in plasma concentrations of citalopram are...
• Clonazepam - Pharmacological action Clonazepam is an antiepileptic drugs from the group of benzodiazepine derivatives. This medication has a pronounced anticonvulsant and central muscle relaxant, anxiolytic, sedative and hypnotic effects. Clonazepam strengthens the inhibitory effect of GABA on the transmission of nerve impulses. Anxiolytic effects of this drug is due to the influence on the amygdaloid complex of the limbic system and appears in reducing the emotional stress, reduce anxiety, fear,...
• Clonazepam-R - Pharmacological action Clonazepam-R is an antiepileptic drugs from the group of benzodiazepine derivatives. This medication has a pronounced anticonvulsant and central muscle relaxant, anxiolytic, sedative and hypnotic effects. Clonazepam strengthens the inhibitory effect of GABA on the transmission of nerve impulses. Anxiolytic effects of this drug is due to the influence on the amygdaloid complex of the limbic system and appears in reducing the emotional stress, reduce anxiety, fear,...
• Fluoxetine - Pharmacological action Fluoxetine is an antidepressant, propylamine derivative. The mechanism of action is associated with selective blockade of the inverse of neuronal serotonin reuptake in the CNS. Fluoxetine is a weak antagonist of choline, adrenergic and histamine receptors. Unlike most antidepressants fluoxetine apparently does not cause reduction of functional activity of postsynaptic beta-adrenergic receptors. This medication improves mood, reduces anxiety and stress, eliminates...
• Gabapentin - Pharmacological action Gabapentin is an antiepileptic drug. Chemical structure is similar to GABA fulfilling the function of the inhibitory neurotransmitter in the CNS. It is believed that the mechanism of action of Gabapentin is different from other anticonvulsants acting through GABA synapses (including valproate, barbiturates, benzodiazepines, inhibitors of GABA-transaminase, inhibitors of GABA capture, GABA agonists and prodrugs of GABA). In in vitro studies showed that Gabapentin is...
• Lisinopril - WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue lisinopril as soon as possible [see Warnings and Precautions (5.1) ]. • Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus [see ...
• Metformin - Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin is the only oral antihyperglycemic agent that is not associated with weight gain. Metformin may induce weight loss and is the drug of choice for obese NIDDM patients. When used alone, metformin does not cause hypoglycemia;...
• Metoprolol-L - Pharmacological action Metoprolol-L Sorres Pharma is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic effect. Metoprolol decreases automaticity of sinus node, reducing heart rate, slows AV-conduction, decreases myocardial contractility and excitability, reduces cardiac output, reduces myocardial oxygen demand. This drug inhibits the stimulatory effect of catecholamines on the heart during...
• Mirtazapine - Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders.  Anyone considering the use of mirtazapine tablets or any other antidepressant in a child, adolescent, or young adult must balance this risk with...
• Ondansetron - Warnings and Precautions, ( 5.3 ) 09/2014 1 INDICATIONS AND USAGE ZUPLENZ is a 5-HT3 receptor antagonist indicated for: ...
• Pantoprazole - Pantoprazole is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. Indication: Short-term (up to 16 weeks) treatment of erosive esophagitis. Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid...
• Paroxetine - Pharmacological action Paroxetine is an antidepressant, selective serotonin reuptake inhibitor. This medication has a bicyclic structure distinct from the structures of other known antidepressants. Paroxetine has antidepressant and anxiolytic effects when expressed enough incentive (activated) effect. Antidepressant (thymoleptic) action is related to the ability of paroxetine selectively block the reuptake of serotonin presynaptic membrane than is caused by increase of free content of...
• Pioglitazone - Pharmacological action Pioglitazone is an oral hypoglycemic agent, series of thiazolidinedione derivatives. Powerful and selective agonist of gamma-receptors, peroxisome proliferator-activated (PPAR-gamma). PPAR-gamma receptors are found in adipose and muscle tissues and liver. Activation of nuclear receptor PPAR-gamma modulates the transcription of several genes that are sensitive to insulin, involved in controlling glucose and lipid metabolism. This medicine reduces insulin resistance in...
• Pravastatin - Pravastatin is a cholesterol-lowering agent that belongs to a class of medications known as statins. It was derived from microbial transformation of mevastatin, the first statin discovered. It is a ring-opened dihydroxyacid with a 6’-hydroxyl group that does not require in vivo activation. Pravastatin is one of the lower potency statins; however, its increased hydrophilicity is thought to confer advantages such as minimal penetration through lipophilic membranes of peripheral cells,...
• Quetiapine - Pharmacological action Quetiapine is an antipsychotic (neuroleptic) drug. This medication exhibits a high affinity for serotonin 5HT2-receptors compared with dopamine D1- and D2-receptors in the brain. Also quetiapine has a high affinity for histamine and alpha1-receptors and a less pronounced - to the alpha2-receptors. This drug has no affinity for the m-cholinergic receptors and benzodiazepine receptors. Quetiapine in the dose effectively blocking dopamine D2-receptors causing only weak...
• Rabeprazole EC
• Risedronate - Risedronate is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget’s disease of bone. Indication: For the treatment of Paget's disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis Risedronate is a pyridinyl bisphosphonate that inhibits osteoclast-mediated bone resorption and modulates bone metabolism and is indicated for the treatment and prevention of osteoporosis in postmenopausal women.
• Risperidone - Risperidone information This medication works well for patients suffering from the agonies of bipolar diseases. Mostly, Risperidone helps individuals with schizophrenia and mania. By affecting the functions of different chemicals in the brain, this drug may provide relief to sufferers. However, before using this drug, patients need to be sure about the side effects that may occur. Risperidone can also be used for treating other disorders or as a complementary drug. Risperidone warnings ...
• Sertraline - Pharmacological action Sertraline (with the generic name of Sertraline) belongs to the groups of drugs known as selective serotonin reuptake inhibitors. These selective serotonin reuptake drugs influence chemical imbalance in the brain responsible for depression, panic anxiety, obsessive compulsive disorder and others. Why is Sertraline prescribed? Sertraline is indicated for the treatment of: depression panic anxiety disorders obsessive compulsive disorder PSTD or post traumatic...
• Simvastatin - Pharmacological action Simvastatin is a hypolipidemic agent from a group of statins, an inhibitor of HMG-CoA reductase. This medication is a prodrug because it has in its structure the closed lactone ring which is hydrolyzed after intake. Lipid-lowering effect of statins is associated with lower levels of total cholesterol by LDL-C. Reducing cholesterol is dose-dependent and is not linear but exponential. Statins do not affect the activity of lipoprotein and hepatic lipase, have no...
• Topiramate - DESCRIPTION Topiramate is a sulfamate-substituted monosaccharide. Topiramate tablets are available as 25 mg, 50 mg, 100 mg, and 200 mg circular tablets for oral administration. Topiramate is a white crystalline powder with a bitter taste. Topiramate USP is most soluble in alkaline solutions containing sodium hydroxide or sodium phosphate and having a pH of 9 to 10. It is freely soluble in acetone, chloroform, dimethylsulfoxide, and ethanol....
• Zopiclone - Pharmacological action Zopiclone is a sleeping drug from group of cyclopyrrolone derivatives. This drug is "non benzodiazepine" agonist of benzodiazepine receptors. Zopiclone also has sedative, anxiolytic, muscle-relaxing center, anticonvulsant and amnesic properties. Like a derivative of benzodiazepine zopiclone enhances GABA-ergic processes in the brain, interacting with the benzodiazepine receptors, as a result of the increased sensitivity of GABA-receptors to the neurotransmitter....

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The information was verified by Dr. Rachana Salvi, MD Pharmacology