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DRUGS & SUPPLEMENTS
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Pharmacol DM
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Pharmacol DM uses
Pharmacol DM consists of Dextromethorphan Hydrobromide, Pheniramine Maleate, Phenylpropanolamine Hydrochloride, Pyrilamine Maleate.Dextromethorphan Hydrobromide:
Pharmacological action
Pharmacol DM is an antitussive medication. Inhibiting the excitability of the cough center this medicine suppresses the cough of any origin. Pharmacol DM (Dextromethorphan Hydrobromide) has not addiction effects and it has no analgesic and hypnotic action. Pharmacol DM (Dextromethorphan Hydrobromide) starts to act after 10-30 minutes after oral administration, the duration of therapeutic action: 5-6 hours for adults and 6-9 hours for children. Pharmacol DM (Dextromethorphan Hydrobromide) is an optical isomer of levomethorphan which is similar to morphine. Due to optical isomerism this drug has no opioid effects. Pharmacol DM (Dextromethorphan Hydrobromide) used mainly for replacement of codeine as a cough suppressant. In addition to the cough suppressant this medication is used in medicine for diagnostic purposes and may be useful in various cases - from seizures to heroin addiction treatment, some chronic neurodegenerative diseases. These include amyotrophic lateral sclerosis (ALS) (Charcot's disease), disease of "mad cow and other prion diseases. Pharmacol DM (Dextromethorphan Hydrobromide) has also been used for the treatment of mental retardation, Parkinson's disease, in the treatment of lung and other cancers and to prevent tissue rejection in transplantation because of the (poorly known) effects of sigma ligands on tumor cells and immune system.
Pharmacokinetics
After oral administration Pharmacol DM (Dextromethorphan Hydrobromide) is completely absorbed from the gastrointestinal tract. Cmax of Pharmacol DM (Dextromethorphan Hydrobromide) in plasma is reached after 2 h. This medication biotransformes in the liver. Up to 45% of this drug is excreted by kidneys and there was considerable individual variation in rates of excretion of individual metabolites.
Why is Pharmacol DM prescribed?
Dry cough of different etiology.
Dosage and administration
For adults and children over 12 years Pharmacol DM prescribed on 15 mg 4 times / day, children aged 6 years - 7.5 mg 4 times / day.
Pharmacol DM (Dextromethorphan Hydrobromide) side effects, adverse reactions
Drowsiness, nausea, dizziness.
Pharmacol DM contraindications
Bronchial asthma, bronchitis, simultaneous reception of mucolytic.
Using during pregnancy and breastfeeding
During pregnancy and lactation (breastfeeding) Pharmacol DM (Dextromethorphan Hydrobromide) prescribed with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk to the fetus or child.
Special instructions
With carefully administered Pharmacol DM (Dextromethorphan Hydrobromide) with impaired liver function.
Pharmacol DM drug interactions
MAO inhibitors (including furazolidone, procarbazine, selegiline) when administered simultaneous with Pharmacol DM (Dextromethorphan Hydrobromide) may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) Pharmacol DM (Dextromethorphan Hydrobromide) may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.
Pharmacol DM in case of emergency / overdose
Symptoms: excitement, dizziness, respiratory depression, impaired consciousness, decreased blood pressure, tachycardia, muscle hypertonicity, ataxia.
Treatment: mechanical ventilation, symptomatic agents.
Pheniramine Maleate:
One of the histamine H1 antagonists with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus.
Indication: Pharmacol DM (Pheniramine Maleate) is an antihistamine used to treat allergic conditions such as hay fever or urticaria.
Pharmacol DM (Pheniramine Maleate) is an antihistamine used to treat allergic conditions such as hay fever or urticaria. It is generally sold in combination with other medications, rather than as a stand-alone drug. Allergies are caused by an excessive type 1 hypersensitivity response of the body to allergens, mediated by inappropriate histamine signalling. By inhibiting the binding of histamine, antihistamines decrease the normal histamine response from cells, consequently decreasing allergic symptoms.
Phenylpropanolamine Hydrochloride:
Pharmacol DM (Phenylpropanolamine Hydrochloride) has been withdrawn in Canada. In November 2000, the Food and Drug Administration (FDA) issued a public health advisory against the use of the drug.
Indication: For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity.
Pharmacol DM (Phenylpropanolamine Hydrochloride) (PPA), a sympathomimetic agent structurally similar to pseudoephedrine, is used to treat nasal congestion. Pharmacol DM (Phenylpropanolamine Hydrochloride) is found in appetite suppressant formulations and with guaifenesinin in cough-cold formulations. In 2000, the FDA requested that all drug companies discontinue marketing products containing Pharmacol DM (Phenylpropanolamine Hydrochloride), due to an increased risk of hemorrhagic stroke in women who used Pharmacol DM (Phenylpropanolamine Hydrochloride).
Pyrilamine Maleate:
For use when an oral antihistamine is needed.
Can be provided to horse: 1/2 ounce (1 tablespoon) per 1000lbs body weight. Can be repeated at 12 hour intervals as needed, or as recommended by a veterinarian. The large end of the enclosed scoop measures 1 tablespoon.
This product contains Pharmacol DM (Pyrilamine Maleate) Maleate which may be prohibited in certain competition. Caution must be taken when used on competition horse subject to drug testing. Check with the event sanction body for the necessary withdrawal time.
EACH OUNCE CONTAINS (minimum): Pharmacol DM (Pyrilamine Maleate) Maleat USP 600mg, in a palatable base.
FOR ANIMAL USE ONLY.
KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.
Keep lid tightly closed and store in a dry place Do not store above 30 C (86 F).
NDC#: 65090-004-15
Pharmacol DM (Pyrilamine Maleate)
Antihistamine Granules
Net Contents: 20 ounces (567 Gm)
Pharmacol DM pharmaceutical active ingredients containing related brand and generic drugs:
Pharmacol DM available forms, composition, doses:
Pharmacol DM destination | category:
Pharmacol DM Anatomical Therapeutic Chemical codes:
Pharmacol DM pharmaceutical companies:
References
- Dailymed."HISTALL (PYRILAMINE MALEATE) GRANULE [AHC PRODUCTS INC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- Dailymed."ADULT WAL TUSSIN COUGH LONG ACTING (DEXTROMETHORPHAN HYDROBROMIDE) SOLUTION [WALGREEN COMPANY]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- Dailymed."PROIN 75 (PHENYLPROPANOLAMINE HYDROCHLORIDE) TABLET, CHEWABLE [PEGASUS LABORATORIES, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Pharmacol DM?Depending on the reaction of the Pharmacol DM after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Pharmacol DM not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Pharmacol DM addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Pharmacol DM, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Pharmacol DM consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
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The information was verified by Dr. Rachana Salvi, MD Pharmacology