Pectobal Dextro

Dextromethorphan Hydrobromide:

• Pharmacological action
• Pharmacokinetics
• Why is Pectobal Dextro prescribed?
• Dosage and administration
• Pectobal Dextro (Dextromethorphan Hydrobromide) side effects, adverse reactions
• Pectobal Dextro contraindications
• Using during pregnancy and breastfeeding
• Special instructions
• Pectobal Dextro drug interactions
• Pectobal Dextro in case of emergency / overdose
• Pectobal Dextro (Dextromethorphan Hydrobromide) reviews

Pharmacological action

Pectobal Dextro is an antitussive medication. Inhibiting the excitability of the cough center this medicine suppresses the cough of any origin. Pectobal Dextro (Dextromethorphan Hydrobromide) has not addiction effects and it has no analgesic and hypnotic action. Pectobal Dextro (Dextromethorphan Hydrobromide) starts to act after 10-30 minutes after oral administration, the duration of therapeutic action: 5-6 hours for adults and 6-9 hours for children. Pectobal Dextro (Dextromethorphan Hydrobromide) is an optical isomer of levomethorphan which is similar to morphine. Due to optical isomerism this drug has no opioid effects. Pectobal Dextro (Dextromethorphan Hydrobromide) used mainly for replacement of codeine as a cough suppressant. In addition to the cough suppressant this medication is used in medicine for diagnostic purposes and may be useful in various cases - from seizures to heroin addiction treatment, some chronic neurodegenerative diseases. These include amyotrophic lateral sclerosis (ALS) (Charcot's disease), disease of "mad cow and other prion diseases. Pectobal Dextro (Dextromethorphan Hydrobromide) has also been used for the treatment of mental retardation, Parkinson's disease, in the treatment of lung and other cancers and to prevent tissue rejection in transplantation because of the (poorly known) effects of sigma ligands on tumor cells and immune system.

Pharmacokinetics

After oral administration Pectobal Dextro (Dextromethorphan Hydrobromide) is completely absorbed from the gastrointestinal tract. C_max of Pectobal Dextro (Dextromethorphan Hydrobromide) in plasma is reached after 2 h. This medication biotransformes in the liver. Up to 45% of this drug is excreted by kidneys and there was considerable individual variation in rates of excretion of individual metabolites.

Why is Pectobal Dextro prescribed?

Dry cough of different etiology.

Dosage and administration

For adults and children over 12 years Pectobal Dextro prescribed on 15 mg 4 times / day, children aged 6 years - 7.5 mg 4 times / day.

Pectobal Dextro (Dextromethorphan Hydrobromide) side effects, adverse reactions

Drowsiness, nausea, dizziness.

Pectobal Dextro contraindications

Bronchial asthma, bronchitis, simultaneous reception of mucolytic.

Using during pregnancy and breastfeeding

During pregnancy and lactation (breastfeeding) Pectobal Dextro (Dextromethorphan Hydrobromide) prescribed with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk to the fetus or child.

Special instructions

With carefully administered Pectobal Dextro (Dextromethorphan Hydrobromide) with impaired liver function.

Pectobal Dextro drug interactions

MAO inhibitors (including furazolidone, procarbazine, selegiline) when administered simultaneous with Pectobal Dextro (Dextromethorphan Hydrobromide) may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) Pectobal Dextro (Dextromethorphan Hydrobromide) may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.

Pectobal Dextro in case of emergency / overdose

Symptoms: excitement, dizziness, respiratory depression, impaired consciousness, decreased blood pressure, tachycardia, muscle hypertonicity, ataxia.

Treatment: mechanical ventilation, symptomatic agents.

Pyrilamine Maleate:

• Pectobal Dextro (Pyrilamine Maleate) reviews

For use when an oral antihistamine is needed.

Can be provided to horse: 1/2 ounce (1 tablespoon) per 1000lbs body weight. Can be repeated at 12 hour intervals as needed, or as recommended by a veterinarian. The large end of the enclosed scoop measures 1 tablespoon.

This product contains Pectobal Dextro (Pyrilamine Maleate) Maleate which may be prohibited in certain competition. Caution must be taken when used on competition horse subject to drug testing. Check with the event sanction body for the necessary withdrawal time.

EACH OUNCE CONTAINS (minimum): Pectobal Dextro (Pyrilamine Maleate) Maleat USP 600mg, in a palatable base.

FOR ANIMAL USE ONLY.

KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.

Keep lid tightly closed and store in a dry place Do not store above 30 C (86 F).

NDC#: 65090-004-15

Pectobal Dextro (Pyrilamine Maleate)

Antihistamine Granules

Net Contents: 20 ounces (567 Gm)