Original Cabdrivers Expectorant

Dextromethorphan Hydrobromide:

• Pharmacological action
• Pharmacokinetics
• Why is Original Cabdrivers Expectorant prescribed?
• Dosage and administration
• Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) side effects, adverse reactions
• Original Cabdrivers Expectorant contraindications
• Using during pregnancy and breastfeeding
• Special instructions
• Original Cabdrivers Expectorant drug interactions
• Original Cabdrivers Expectorant in case of emergency / overdose
• Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) reviews

Pharmacological action

Original Cabdrivers Expectorant is an antitussive medication. Inhibiting the excitability of the cough center this medicine suppresses the cough of any origin. Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) has not addiction effects and it has no analgesic and hypnotic action. Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) starts to act after 10-30 minutes after oral administration, the duration of therapeutic action: 5-6 hours for adults and 6-9 hours for children. Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) is an optical isomer of levomethorphan which is similar to morphine. Due to optical isomerism this drug has no opioid effects. Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) used mainly for replacement of codeine as a cough suppressant. In addition to the cough suppressant this medication is used in medicine for diagnostic purposes and may be useful in various cases - from seizures to heroin addiction treatment, some chronic neurodegenerative diseases. These include amyotrophic lateral sclerosis (ALS) (Charcot's disease), disease of "mad cow and other prion diseases. Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) has also been used for the treatment of mental retardation, Parkinson's disease, in the treatment of lung and other cancers and to prevent tissue rejection in transplantation because of the (poorly known) effects of sigma ligands on tumor cells and immune system.

Pharmacokinetics

After oral administration Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) is completely absorbed from the gastrointestinal tract. C_max of Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) in plasma is reached after 2 h. This medication biotransformes in the liver. Up to 45% of this drug is excreted by kidneys and there was considerable individual variation in rates of excretion of individual metabolites.

Why is Original Cabdrivers Expectorant prescribed?

Dry cough of different etiology.

Dosage and administration

For adults and children over 12 years Original Cabdrivers Expectorant prescribed on 15 mg 4 times / day, children aged 6 years - 7.5 mg 4 times / day.

Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) side effects, adverse reactions

Drowsiness, nausea, dizziness.

Original Cabdrivers Expectorant contraindications

Bronchial asthma, bronchitis, simultaneous reception of mucolytic.

Using during pregnancy and breastfeeding

During pregnancy and lactation (breastfeeding) Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) prescribed with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk to the fetus or child.

Special instructions

With carefully administered Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) with impaired liver function.

Original Cabdrivers Expectorant drug interactions

MAO inhibitors (including furazolidone, procarbazine, selegiline) when administered simultaneous with Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) Original Cabdrivers Expectorant (Dextromethorphan Hydrobromide) may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.

Original Cabdrivers Expectorant in case of emergency / overdose

Symptoms: excitement, dizziness, respiratory depression, impaired consciousness, decreased blood pressure, tachycardia, muscle hypertonicity, ataxia.

Treatment: mechanical ventilation, symptomatic agents.

Menthol:

• Original Cabdrivers Expectorant (Menthol) reviews

Indication: Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.

Original Cabdrivers Expectorant (Menthol) is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Menthol's ability to chemically trigger cold-sensitive receptors in the skin is responsible for the well known cooling sensation that it provokes when inhalated, eaten, or applied to the skin. It should be noted that Original Cabdrivers Expectorant (Menthol) does not cause an actual drop in temperature.