Quest Plus

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Quest Plus Oral Gel

Contains 20 mg moxidectin/mL (2.0% w/v)

and 125 mg praziquantel/mL (12.5% w/v)

DEWORMER & BOTICIDE

FOR ORAL USE IN HORSES AND PONIES

SIX MONTHS OF AGE AND OLDER

INDICATIONS

Quest Plus (moxidectin/praziquantel) Equine Oral Gel when administered at the recommended dose level of 0.4 mg moxidectin/kg and 2.5 mg praziquantel/kg (2.2 lb) body weight is effective in the treatment and control of the following stages of gastrointestinal parasites in horses and ponies:

Large Strongyles

Small Strongyles

Small Strongyles

Encysted cyathostomes

Ascarids

Pinworms

Hairworms

Large-mouth stomach worms

Horse stomach bots

Tapeworms


One administration of the recommended dose rate of Quest Plus (moxidectin/praziquantel) Equine Oral Gel also suppresses strongyle egg production through 84 days.

STRATEGIC PROTECTION PROGRAMS

Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. For best control of parasites, all horses and ponies should be included in a strategic treatment program, with particular attention given to high performance animals. In foals, initial treatment is recommended at 6 months of age, after which they should be included in a recurrent treatment program. Because Quest Plus provides effective control of the mucosal stages of small strongyles (encysted cyathostomes) and tapeworms, it is useful in reducing the frequency of treatment required for successful strategic equine parasite control. A veterinarian can assist in preparing the best program for your needs.

Quest Plus Equine Oral Gel when used at the recommended dose rate suppresses strongyle egg production through 84 days following a single oral administration. This residual strongyle control reduces pasture contamination and provides a period of protection from reinfection for horses and ponies maintained on the same pasture.

MODE OF ACTION

Quest Plus Equine Oral Gel contains two active pharmaceutical ingredients, Quest Plus and praziquantel. Quest Plus acts by interfering with chloride channel-mediated neurotransmission in the parasite. This results in paralysis and elimination of the parasite. Quest Plus is safe for use in horses and ponies because it does not have the same injurious effect on the mammalian nervous system. Praziquantel increases the tapeworm's membrane permeability to calcium and other cations causing severe contraction and paralysis of the tapeworm's muscles. This spastic paralysis results in the inability of tapeworms to attach to the host's intestinal wall. Detached tapeworms are either destroyed by the host's immune defense system or passed in the feces.

ADMINISTRATION AND DOSAGE

Quest Plus (moxidectin/praziquantel) Equine Oral Gel is specially formulated as a palatable gel which is easily administered to horses and ponies. Quest Plus Gel is packaged in ready-touse SURE-DIAL® syringes (see diagram of the SURE-DIAL® syringe). The syringe is calibrated in 50-pound increments, up to 1250 pounds. This enables the administration of the recommended dose level by choosing a setting consistent with the animal's weight.

HOW TO SET THE DOSE

Since the dose is based on the weight of the animal, you need to use a scale or weight tape to find each animal's weight before treating with Quest Plus Gel. Once the weight is known, set the dose for each horse or pony as follows.

HOW TO GIVE Quest Plus GEL TO A HORSE OR PONY

TREATING A SECOND HORSE OR PONY WITH THE SAME SYRINGE

If the first animal you treat weighs less than 1250 lbs., there will be gel left in the syringe. You can use this gel to treat other horses or ponies. To set the next dose, add the weight of the animal you want to treat to the dose setting already on the syringe. For example, if the syringe was first used to treat a 250 lb. animal, the blue dial ring is set on 250 lbs. To treat a 500 lb. animal next, move the blue dial ring to the 750 lb. marking (250+500=750). You need more than one syringe to treat horses weighing more than 1250 lbs.

Each syringe of Quest Plus Equine Oral Gel may be used to treat more than one animal especially when dosing ponies and growing and lighter breeds of horses. The following table will help estimate the number of horses or ponies the contents of each syringe will treat.

Ponies Light Horses Heavy Horses
Weight Treated Animals Weight Treated Animals Weight Treated Animals
Age (lbs) (kg) (per syringe) (lbs) (kg) (per syringe) (lbs) (kg) (per syringe)
6 months 200 (91) 6 400 (181) 3 550 (250) 2
9 months 250 (113) 5 500 (227) 2 700 (318) 1
Mature 450 (204) 2 900 (409) 1 1300 (590) A full syringe plus a portion of a second syringe is required to treat horses weighing more than 1250 lb.

ANIMAL SAFETY

Quest Plus (moxidectin/praziquantel) Equine Oral Gel can be safely administered at the recommended dose to horses and ponies of all breeds at least 6 months of age and older. Transient ataxia, incoordination, lethargy, depression and droopy lips and eyelids may be seen when very young or debilitated animals are treated. In these instances, supportive care may be advisable. Reproductive studies evaluating the safety of Quest Plus in mares at or near the time of breeding, pregnant mares and breeding stallions have not been conducted.

To report adverse drug reactions or to obtain a copy of the Material Safety Data Sheet (MSDS) call call 1-888-963-8471.

ENVIRONMENTAL SAFETY

Care should be taken to avoid the release of significant volumes of this product into either ground or free-running water since Quest Plus may be injurious to aquatic life. SURE-DIAL® syringes and their contents should be disposed of in an approved landfill or by incineration.

PRECAUTIONS

Quest Plus Equine Oral Gel has been formulated specifically for use in horses and ponies only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.

WARNINGS

Extreme caution should be used when administering the product to foals, young and miniature horses, as overdosage may result in serious adverse reactions. Do not use in sick, debilitated, or underweight animals. Do not use in horses intended for human consumption.

HUMAN WARNINGS

Not for use in humans. Keep this and all drugs out of the reach of children. Do not ingest. If swallowed, induce vomiting. Wash hands and contaminated skin with soap and water. If accidental contact with eyes occurs, flush repeatedly with water. If irritation or any other symptom attributable to exposure to this product persists, consult your physician.

HOW SUPPLIED

Quest Plus Equine Oral Gel is available in one syringe applicator size.

Each SURE-DIAL® syringe contains 0.4 oz (11.6 g) of Quest Plus Equine Oral Gel which is sufficient to treat a single horse weighing up to 1250 lb, or two or more lighter animals with a combined body weight of up to 1250 lb.

0.4 oz (11.6 g) syringe - 20 mg Quest Plus and 125 mg praziquantel per mL

Store at or below 77°F (25°C). Avoid freezing. If frozen, thaw completely before use. Store partially-used syringes with the cap tightly secured.

Syringe

Distributed by:

Zoetis Inc.

Kalamazoo, MI 49007

Made in Spain

Revised: January 2013

P1103-525US/02-12

NADA 141-216, Approved by FDA

Quest Plus pharmaceutical active ingredients containing related brand and generic drugs:


Quest Plus available forms, composition, doses:


Quest Plus destination | category:


Quest Plus Anatomical Therapeutic Chemical codes:


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References

  1. Dailymed."TAPEWORM DEWORMER FOR DOGS (PRAZIQUANTEL) TABLET [BAYER HEALTHCARE, LLC ANIMAL HEALTH DIVISION]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."CYDECTIN POUR-ON FOR BEEF AND DAIRY CATTLE (MOXIDECTIN) LIQUID [BAYER HEALTHCARE, LLC ANIMAL HEALTH DIVISION]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. Dailymed."PRAZIQUANTEL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Quest Plus?

Depending on the reaction of the Quest Plus after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Quest Plus not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Quest Plus addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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