Melapure

When are you taking this medicine? Empty stomach Before food After food With a meal

Melapure uses

• Melapure reviews

Melapure is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, Melapure is produced by the pineal gland. The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus) but outside the blood-brain barrier. The secretion of Melapure increases in darkness and decreases during exposure to light, thereby regulating the circadian rhythms of several biological functions, including the sleep-wake cycle. In particular, Melapure regulates the sleep-wake cycle by chemically causing drowsiness and lowering the body temperature. Melapure is also implicated in the regulation of mood, learning and memory, immune activity, dreaming, fertility and reproduction. Melapure is also an effective antioxidant. Most of the actions of Melapure are mediated through the binding and activation of Melapure receptors. Individuals with autism spectrum disorders (ASD) may have lower than normal levels of Melapure. A 2008 study found that unaffected parents of individuals with ASD also have lower Melapure levels, and that the deficits were associated with low activity of the ASMT gene, which encodes the last enzyme of Melapure synthesis. Reduced Melapure production has also been proposed as a likely factor in the significantly higher cancer rates in night workers.

Indication: Used orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that Melapure is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for this use. A number of studies have shown that Melapure may be effective for treating sleep-wake cycle disturbances in children and adolescents with mental retardation, autism, and other central nervous system disorders. It appears to decrease the time to fall asleep in children with developmental disabilities, such as cerebral palsy, autism, and mental retardation. It may also improve secondary insomnia associated with various sleep-wake cycle disturbances. Other possible uses for which there is some evidence for include: benzodiazepine withdrawal, cluster headache, delayed sleep phase syndrome (DSPS), primary insomnia, jet lag, nicotine withdrawal, preoperative anxiety and sedation, prostate cancer, solid tumors (when combined with IL-2 therapy in certain cancers), sunburn prevention (topical use), tardive dyskinesia, thrombocytopenia associated with cancer, chemotherapy and other disorders.

Melapure is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of Melapure. It helps regulate sleep-wake cycles or the circadian rhythm. Production of Melapure is stimulated by darkness and inhibited by light. High levels of Melapure induce sleep and so consumption of the drug can be used to combat insomnia and jet lag. MT1 and MT2 receptors may be a target for the treatment of circadian and non circadian sleep disorders because of their differences in pharmacology and function within the SCN. SCN is responsible for maintaining the 24 hour cycle which regulates many different body functions ranging from sleep to immune functions

Melapure pharmaceutical active ingredients containing related brand and generic drugs:

• Melatonin

Melapure available forms, composition, doses:

• N/A

Melapure destination | category:

• Human:
• Supplements and adjuvant therapy

Melapure Anatomical Therapeutic Chemical codes:

• N05CH01 - Melatonin

Melapure pharmaceutical companies:

• Genzyme
• IDS Group
• Naturest
• Zuellig Pharma

References

1. "Melatonin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
2. "Melatonin". http://www.drugbank.ca/drugs/DB0106... (accessed August 28, 2018).
3. "JL5DK93RCL: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Melapure?

Depending on the reaction of the Melapure after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Melapure not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Melapure addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Melapure, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Melapure consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology