Terramycin Plus

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Terramycin Plus uses

• Description
• Actions
• Indications
• Contraindications
• Warnings
• Precautions
• Adverse reactions
• Dosage and administration
• Caution
• How supplied
• Terramycin Plus reviews

STERILE - ANTIBACTERIAL

NADA # 065-015. Approved by FDA.

DESCRIPTION

Each gram contains Terramycin Plus 400 units, Neomycin Sulfate 5 mg (equivalent to 3.5 mg of Neomycin base), Polymyxin B Sulfate 10,000 units, Hydrocortisone Acetate 10 mg (1 %), in a base of White Petrolatum and Mineral Oil.

ACTIONS

The overlapping spectra of these three antibiotics provide effective bactericidal action against most commonly occurring gram-positive and gram-negative bacteria associated with infections of the eyes. The range of bactericidal activity encompasses many bacteria which are, or have become, resistant to other antibiotics, notably Pseudomonas and Staphylococcus. In susceptible organisms, resistance rarely develops, even on repeated or prolonged usage. Hydrocortisone acetate exerts a marked anti-inflammatory action at the tissue level and effectively suppresses inflammation in many disorders of the anterior segment of the eye. Local application to the eye often gives rapid relief of pain and photophobia, particularly in lesions of the cornea.

The combined anti-inflammatory and antimicrobial activity of Vetropolycin ® HC (bacitracin-neomycin-polymyxin-hydrocortisone acetate 1%) veterinary ophthalmic ointment permits effective management of many disorders of the anterior segment of the eye in which combined activity is needed.

INDICATIONS

It may be used in acute or chronic conjunctivitis, when caused by organisms susceptible to the antibiotics contained in this ointment. Laboratory tests should be conducted including in vitro culturing and susceptibility tests on samples collected prior to treatment.

CONTRAINDICATIONS

Ophthalmic preparations containing corticosteroids are contraindicated in the treatment of those deep, ulcerative lesions of the cornea where the inner layer (endothelium) is involved, in fungal infections and in the presence of viral infections.

WARNINGS

All topical ophthalmic preparations containing corticosteroids with or without an antimicrobial agent, are contraindicated in the initial treatment of corneal ulcers. They should not be used until the infection is under control and corneal regeneration is well under way.

Clinical and experimental data have demonstrated that corticosteroids administered orally or by injection to animals may induce the first stage of parturition if used during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis.

Additionally, corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring.

Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia, and anasarca.

PRECAUTIONS

Sensitivity to this ophthalmic ointment is rare, however, if a reaction occurs, discontinue use of the preparation.

The prolonged use of antibiotic-containing preparations may result in overgrowth of nonsusceptible organisms including fungi. Appropriate measures should be taken if this occurs. If infection does not respond to treatment in two or three days, the diagnosis and therapy should be reevaluated. Animals under treatment with this product should be observed for usual signs of corticosteroid overdose which include polydipsia, polyuria and occasionally an increase in weight.

Use of corticosteroids, depending on dose, duration, and specific steroid, may result in inhibition of endogenous steroid production following drug withdrawal. In patients presently receiving or recently withdrawn from systemic corticosteroid treatments, therapy with a rapidly acting corticosteroid should be considered in unusually stressful situations. Care should be taken not to contaminate the applicator tip during administration of the preparation.

ADVERSE REACTIONS

Itching, burning or inflammation may occur in animals sensitive to the product. Discontinue use in such cases.

SAP and SGPT (All) enzyme elevations, polydypsia and polyuria have occurred following parenteral or systemic use of synthetic corticosteroids in dogs. Vomiting and diarrhea (occasionally bloody) have been observed in dogs.

Cushings syndrome in dogs has been reported in association with prolonged or repeated steroid therapy.

DOSAGE AND ADMINISTRATION

Apply a thin film over the cornea three or four times daily. The area to be treated should be properly cleansed prior to use. Foreign bodies, crusted exudates and debris should be carefully removed. Insert the tip of the tube beneath the lower lid and express a small quantity of the ointment into the conjunctiva! sac in dogs and cats.

CAUTION

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

HOW SUPPLIED

3.5 g (1/8 Oz) sterile tamper proof tubes. NDC 17033-030-38.

STORE AT 15°-25°C (59°-77°F).

Manufactured for:

Dechra Veterinary Products

Overland Park, KS 66211.

lni0912

R1112

Terramycin Plus pharmaceutical active ingredients containing related brand and generic drugs:

• Bacitracin Zinc
• Neomycin Sulfate
• Polymyxin B Sulfate

Terramycin Plus available forms, composition, doses:

• Ointment; Topical; Bacitracin Zinc 10 mg; Neomycin Sulfate 5 mg; Polymyxin B Sulfate 0.71 mg / g

Terramycin Plus destination | category:

• Human:
• Antibacterials
• Antibiotics
• Bacitracins
• Topical antibiotics used in the treatment of dermatological diseases

Terramycin Plus Anatomical Therapeutic Chemical codes:

• D06AX30 - Combinations of antibiotics
• S01AA30 - Combinations of different antibiotics

Terramycin Plus pharmaceutical companies:

• Pfizer
• Zuellig Pharma

References

1. Dailymed."CAREALL BACITRACIN (BACITRACIN ZINC) CREAM [NEW WORLD IMPORTS, INC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
2. Dailymed."NEOMYCIN SULFATE TABLET [LANNETT COMPANY, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
3. Dailymed."BACITRACIN ZINC; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).

Frequently asked Questions

Depending on the reaction of the Terramycin Plus after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Terramycin Plus not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology