DRUGS & SUPPLEMENTS

Strattera

Name: Strattera drug & pharmaceuticals. Available Forms, Doses, Prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

What is the dose of the medication you are taking?

Strattera uses

Pharmacological action
Pharmacokinetics
Why is Strattera prescribed?
Dosage and administration
Strattera side effects, adverse reactions
Strattera contraindications
Using during pregnancy and breastfeeding
Special instructions
Strattera drug interactions
Strattera in case of emergency / overdose
Strattera reviews

Pharmacological action

Strattera is a centrally acting sympathomimetic. This medication is highly selective potent inhibitor of presynaptic norepinephrine transporters. Strattera has minimal affinity to the other noradrenergic receptors or to other transporters or receptors of neurotransmitters.

This drug does not apply to psychostimulants and it is not a derivative of amphetamine. In clinical trials there were not noted of increase symptoms or any adverse events associated with withdrawal syndrome.

Pharmacokinetics

After oral administration Strattera is quickly and almost completely absorbed, reaching a C_max in the plasma of approximately 1-2 hours. This medication is well distributed in the body. It has a high affinity for plasma proteins, primarily to albumin. The average T_1/2 of Strattera after oral administration is 3.6 hours in patients with severe metabolism and 21 hours in patients with decreased metabolism. This drug is mainly excreted in the urine.

Why is Strattera prescribed?

Attention Deficit Hyperactivity Disorder in children 6 years and older, adolescents and adults.

Dosage and administration

Strattera is taken orally regardless of the meal or during a meal, as a single daily dose in the morning. In the case of adverse reactions while taking the drug 1 time / day, patients can be recommended to receive doses 2 times / day, dividing the dose by levee and reception late in the afternoon or early evening.

For children and adolescents weighing 70 kg the recommended initial daily dose is about 0.5 mg / kg and increased to a therapeutic daily dose of about 1.2 mg / kg no sooner than 3 days. In the absence of improvement of the patient's total daily dose may be increased to a maximum dose of 1.8 mg / kg no sooner than 2-4 weeks after starting treatment. The recommended maintenance dose is approximately 1.2 mg / kg / day. The recommended maximum daily dose is 1.8 mg / kg or 120 mg.

For children and adolescents weighing over 70 kg and adults the recommended initial daily dose is 40 mg and increased to a therapeutic daily dose of 80 mg no earlier than 3 days. In the absence of improvement of the patient's total daily dose may be increased to a maximum dose of 120 mg did not earlier than 2-4 weeks after starting treatment. The recommended maintenance dose is 80 mg. The recommended maximum daily dose is 120 mg.

Strattera side effects, adverse reactions

Side effects in patients with poor metabolism: loss of appetite, insomnia, impaired quality of sleep, enuresis, poor mood, tremor, early morning awakening, conjunctivitis, syncope, mydriasis.

Digestive system: very often - loss of appetite, dry mouth, nausea; often - abdominal pain, constipation, dyspepsia, flatulence.

CNS: very often - insomnia; often - early morning awakening, decreased libido, insomnia, dizziness, impaired sleep quality, sinus headache, drowsiness.

Cardiovascular system: often - hot flashes of blood, palpitations, tachycardia; sometimes - the feeling of coldness in the lower extremities; very rare - peripheral vascular reactions and / or Raynaud's syndrome and Raynaud's syndrome risk of relapse.

Urinary system: often - difficulty urinating, urinary retention.

Reproductive system: often - dysmenorrhea, abnormal ejaculation, lack of ejaculation, erectile dysfunction, erectile dysfunction, menstrual disorders, impaired orgasm, prostate; very rare - according to spontaneous reports, a painful or prolonged erection.

Dermatological reactions: often - dermatitis, excessive sweating.

Other: often - fatigue, chills, weight loss.

Strattera contraindications

The simultaneous use of MAO inhibitors, angle-closure glaucoma, increased sensitivity to Strattera.

Using during pregnancy and breastfeeding

The use of Strattera pregnancy and lactation is possible only if the expected benefit of therapy to the mother far outweighs the potential risk to the fetus or infant.

It is not known whether Strattera excreted in breast milk in humans.

Special instructions

Use Strattera with caution in patients with hypertension, tachycardia, with cardiovascular disease, violation of cerebral circulation, as well as any condition which may lead to hypotension, since reported cases of orthostatic hypotension.

This medication can cause arterial hypertension in patients with end-stage renal disease.

ADHD symptoms as impaired attention and hyperactivity may been showed as impairment of concentration, distractibility, excessive restlessness, impulsiveness, disorganization, restlessness, and other similar conduct disorder. The diagnosis of ADHD must meet the criteria for ICD-10.

In clinical studies in children and adolescents during treatment with this medicine there was increased a risk of suicidal thoughts.

In rare cases, patients taking Strattera observed allergic reactions - rashes, angioedema, urticaria.

This drug should not be used for at least 2 weeks after discontinuation of MAO inhibitors. Treatment of MAO inhibitors should not be initiated within 2 weeks after discontinuation of Strattera.

Many patients taking atomoksetin, there was some increase in heart rate and / or increased blood pressure (an average of < 5 mm Hg). In most cases, these changes were not clinically significant effect. Also there were cases of orthostatic hypotension.

In patients with manifestations of jaundice or laboratory parameters identified which indicate liver dysfunction this medication should be abolished.

Patients (especially children and teenagers) who are receiving treatment for ADHD should be monitored for the onset of aggressive behavior or hostility.

Patients receiving Strattera require supervision due to risk of occurrence of the following symptoms: anxiety, agitation, panic attacks, insomnia, irritability, impulsivity, akathisia, hypomania and mania.

Strattera drug interactions

When this drug applied simultaneously with agonists of beta2-adrenergic receptors it may been increase their effects on the cardiovascular system (this combination should be used with caution).

In patients with severe metabolism CYP2D6 inhibitors increase the content of CYP2D6 Strattera in plasma at steady state to a level similar to that in patients with decreased metabolism of CYP2D6.

When Strattera used with drugs affecting blood pressure it may been changes in blood pressure.

Strattera in case of emergency / overdose

Symptoms: drowsiness, agitation, hyperactivity, behavioral disorders, gastrointestinal dysfunction, mydriasis, tachycardia, dry mouth, seizures.

Treatment: gastric lavage, activated charcoal, control of the heart and vital signs, ventilation, symptomatic and supportive therapy. Hemodialysis is ineffective.

Strattera pharmaceutical active ingredients containing related brand and generic drugs:

Atomoxetine Hydrochloride

Strattera available forms, composition, doses:

Capsules; Oral; Atomoxetine Hydrochloride 10 mg
Capsules; Oral; Atomoxetine Hydrochloride 100 mg
Capsules; Oral; Atomoxetine Hydrochloride 18 mg
Capsules; Oral; Atomoxetine Hydrochloride 25 mg
Capsules; Oral; Atomoxetine Hydrochloride 40 mg
Capsules; Oral; Atomoxetine Hydrochloride 5 mg
Capsules; Oral; Atomoxetine Hydrochloride 60 mg
Capsules; Oral; Atomoxetine Hydrochloride 80 mg

Strattera destination | category:

Human:
CNS drugs and agents for ADHD
Central nervous system agents

Strattera Anatomical Therapeutic Chemical codes:

N06BA09 - Atomoxetine

Strattera pharmaceutical companies:

References

Dailymed."STRATTERA (ATOMOXETINE HYDROCHLORIDE) CAPSULE STRATTERA (ATOMOXETINE HYDROCHLORIDE) KIT [ELI LILLY AND COMPANY". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"Atomoxetine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"Atomoxetine". http://www.drugbank.ca/drugs/DB0028... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Strattera?

Depending on the reaction of the Strattera after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Strattera not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Strattera addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Strattera, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Strattera consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.